In FO4 you can run into a Yao Guai within ten minutes of exiting Vault 111 if you wander to the right spot. And if you do, and you haven't picked up a powerful early game weapon, you will instantly learn things about a bear ghoul's digestive system you really didn't want to know.
I'm still experimenting with grayscale stuff. It has the advantage of being quick to do and I do like pencil work a lot lately.