The original sketch was created by the one and only General Irrelivant.
For those who are not privy to the joke; Eli, the pony hanging from basketball hoop has a rule by her owner that everything is canon - EVERYTHING.
So insert a 1990's Tremors reference with Non Toxic, Berry and Ahriannah an you have this meme.
Eli: Why does THIS have to be canon?
Ahriannah: I've got another stick of VEGEMITE! - GET READY TO RUN!
Berry: I've seen enough hentai to know where this is going.
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~KEZ