A personal thought I've had for a very long time was on the subject of alternate universes in videogames, where the villain character was the hero and the her character was the villain. Delta and Blaze helped me out with the designs for many of these characters, so credit to them for a lot of the lineart on these!
This is Cortex, taking some design influences from Tony Stark (a.k.a. Iron Man) and the power gauntlets seen used by Dexter in Powerpuff Girls Doujinshi.