So I've been playing a lot of Binding of Isaac: Rebirth. I blame my significant other.

When I unlocked the Negative, I defeated Satan with Samson who had Lord of the Pit and Brimstone by the end of the game. It was pretty insane with how much damage I was doing and I killed Satan in nearly two brimstone shots.

If you haven't checked out the game, you should! It's tons of fun, but it's pretty creepy and strange too.