This image was painted for a game-developer girl who endured a horrifying hit-and-run motorcycle crash a few years ago. She lost her leg, but managed to survive the pain and grief caused by the accident.
She had a fan-crush on Pinkie Pie during that time.
Since then she's recovered well and is working at a pretty awesome game studio. To me, that is a notable feat. Overcoming adversity should be a way of life to everyone. Never let your misfortune swallow you whole - and even in the face of death, you must keep moving.
You can literally transform your world by identifying and attacking the problems that you have, find strength, and give strength to others in the process.