An idea from highschool inspired by Dead Space (my favorite game) that features a lost space (wo)man locked inside the Arno, a military space cruiser that is brimming with recently released extraterrestrial creatures. (S)He partners with the ships battalion of droids to help in h(er)is escape back home.
The story Arno is a continuation of the arc of Ozzy/Oswald who has excelled to the career of a space explorer.