In case you cant read the text:
Malivous: I hate you Orochi
Orochigami: Oh come on its just a joke

2nd panel
Salarian: What is that Turian doing over there?
Dieze: Oh hes just talking to his snake
Malivous in the background: No I hate you, how dare you do that
Salarian: Wait you mean...

3rd panel
Malivous in the background: I'm going to kill you you...damn snake
Salarian: HIS JOHNSON!?

If you dont get it, Johnson is another term of word for penis and of course Orochigami has the ability to be seen by those he wants to be seen by, example Dieze and Jiv, but he often likes to appear not there in public hence why this poor Salarian was rather confused by the situation.

Oh and the prank Orochigami pulled you ask? He made Mal trip over when he wasn't looking.